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http://nopr.niscpr.res.in/handle/123456789/9206| Title: | Clean and efficient microwave solvent-free synthesis of some antimicrobial compounds from 2-aminothiadiazine |
| Authors: | Patel, V M Desai, K R |
| Keywords: | Microwave irradiation;antimicrobial activity;2-aminothiadiazine |
| Issue Date: | Oct-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D // A 61 P 31/04 |
| Abstract: | A series of 1-[5΄-(2, 4-dichloro-5-fluorophenyl)-6΄H-1΄, 3΄, 4΄-thiadiazin-2΄-yl]-4-(substituted phenyl)-3-chloro-2-oxo-azetidines 3 and 3-[5΄-(2, 4-dichloro-5-fluorophenyl)-6΄H-1΄,3΄,4΄-thiadiazin-2΄-yl]-2-(substituted phenyl)-1, 3-thiazolidin-4-one 4 have been synthesized using environmentally benign procedure and evaluated for their antimicrobial activity. Neat reactants are subjected to microwave irradiation under solvent-free condition. The observed yields and enhancement in reaction rates are due to the solvent-free conditions coupled with microwave usage. Structures of the synthesized compounds have been elucidated on the basis of their elemental analyses and spectral data. |
| Page(s): | 2158-2162 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.44B(10) [October 2005] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 44B(10) 2158-2162.pdf | 148.46 kB | Adobe PDF | View/Open |
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