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http://nopr.niscpr.res.in/handle/123456789/11404| Title: | Facile one-pot synthesis of novel 3-substituted-1, 6-dihydro-1,2,4-triazin-5-(2H)-ones from fatty acid hydrazides and their in-vitro antimicrobial activity |
| Authors: | Farshori, Nida Nayyar Banday, Mudasir Rashid Ahmad, Anis Khan, Asad Ullah Rauf, Abdul |
| Keywords: | Fatty acid hydrazides;1,2,4-triazin-5-ones;IR;1H NMR;MS;Antimicrobial activity |
| Issue Date: | Apr-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A series of 3-substituted-1,6-dihydro-1,2,4-triazin-5(2H)-ones, have been synthesized using the cyclocondensation reaction of fatty acid hydrazides with 2-chloroacetamide in N,N-dimethylformamide medium. The structural elucidation of the synthesized compounds is based on IR, 1H NMR, mass spectral data and elemental analysis. These compounds have been tested for their in-vitro antibacterial and antifungal activities. The MIC, MBC and MFC have also been determined. |
| Page(s): | 605-610 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.50B(04) [April 2011] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 50B(4) 605-610.pdf | 87.87 kB | Adobe PDF | View/Open |
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