Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/11446| Title: | Codon usage pattern of differentially expressed genes in Leishmania species |
| Authors: | Singh, Abhimanyu Kumar Vidyarthi, Ambarish Sharan Shankaracharya |
| Keywords: | Effective number of codons;Leishmania infantum;L. major;Mutational pressure;Relative synonymous codon usage;Translational selection |
| Issue Date: | Apr-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Out of numerous genes, differentially expressed genes of Leishmania major (299) and L. infantum (241), essential for their survival, have been studied for the analysis of synonymous codon usage patterns. The role of translational selection and mutational biases were analyzed through ENc plot and correspondence analysis. Present analysis indicates that mutational pressure has a profound effect on codon usage pattern in both the species of Leishmania (with a minor variation). Beside this, natural and translational selections also operate with a proper balance that makes the organism translationally more efficient. |
| Page(s): | 188-195 |
| ISSN: | 0975-0967 (Online); 0972-5849 (Print) |
| Appears in Collections: | IJBT Vol.10(2) [April 2011] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJBT 10(2) 188-195.pdf | 166.24 kB | Adobe PDF | View/Open |
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