Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/16469
Title: Synthesis and antibacterial activity of 4-aryl-1-(1-p-chlorophenyl-5-methyl- 1,2,3-triazol-4-carbonyl)thiosemicarbazides and their related heterocyclic derivatives
Authors: Sun, Xiao-Wen
Liang, Hong-Taoq
Zhang, Zi-Yi
Wang, Qin
Wang, Fang
Issue Date: Jun-1999
Publisher: NISCAIR-CSIR, India
Abstract: A series of new 2-arylamino-5-(1-p-chlorophenyl-5-methyl-1,2,3-triazol-4-yl)-1 ,3,4-thiadiazoles 5a-d, 4-aryl-3-(1-p-chlorophenyl-5-methyl-1,2,3-triazol-4-yl)-1,2,4-triazolin-5-thiones 6a-e, 2-arylamino-5-( 1-p-chlorophenyl-5-methyl-1.2,3-triazol-4-yl)-1 ,3,4-oxadiazoles 7a-d have been synthesized by the intramolecular cyclization of 4-aryl-1-( 1-p-chlorophenyl-5-methyl-1,2,3-triazol-4-carbonyl)thiosemicarbazides 4a-e with cone. H2S04, 2N  NaOH and NaOAc-HOAc solution, respectively. Supports for the structures of the synthesized compounds have been provided by their elemental analyses and spectral data. The representative compounds are evaluated for their antibacterial activity.
Page(s): 679-683
Appears in Collections:IJC-B Vol.38B(06) [June 1999]

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