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http://nopr.niscpr.res.in/handle/123456789/16989| Title: | Role of 5-hydroxytryptamine in Moringa oleifera induced potentiation of pentobarbitone hypnosis in albino rats |
| Authors: | Ray, Kausik Hazra, Rimi Debnath, Pratip Kr Guha, Debjani |
| Keywords: | Moringa oleifera;PB sleeping time;Serotonin;EEG |
| Issue Date: | Jun-2004 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The role of 5-hydroxytryptamine (5-HT) in pentobarbitone (PB ) sleeping time, gross behaviour, electrical activity of the brain and serum 5-HT level was studied in Holtzman strain adult albino rats following treatment with M. oleifera (MO). MO (350mg/kg) caused inhibition of awareness, touch response, motor activity, righting reflex, and grip strength. It significantly increased the PB sleeping time, serum 5-HT level (P<0.001) and α-wave activity. These observations indicate that the aqueous extract of MO potentiated PB induced sleeping time and increased the α-wave activity through 5-HT. |
| Page(s): | 632-635 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.42(06) [June 2004] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 42(6) 632-635.pdf | 1.03 MB | Adobe PDF | View/Open |
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