Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/19168
Title: Coordinate production of cephamycin c and clavulanic acid by Streptomyces clavuligerus
Authors: Thakur, R
Roy, M K
Dutta, N N
Bezbaruah, R L
Issue Date: Oct-1999
Publisher: NISCAIR-CSIR, India
Abstract: Production of cephamycin c and clavulanic acid by Streptomyces clavuligerus was investigated using different media in shake flask condition. Highest cell growth (3.8 g/L) was observed in glycerol, sucrose, proline and glutamic acid (GSPG) medium. Although, GSPG medium supported maximum growth, it was least effective for the synthesis of both cephamycin and clavulanic acid. Yield of cephamycin and clavulanic acid was maximum in dextrin and K medium. resrectively. High and low level of constituents of dextrin medium, affected production of both cephamycin and clavulanic acid. Biosynthesis of clavulanic acid was associated with production of cephamycin c.
Page(s): 1031-1033
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.37(10) [October 1999]

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