Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/20220| Title: | Solvent effects on alkaline hydrolysis of N-benzylphthalimide in mixed water-acetonitrile and mixed water-N,N-dimethylformamide |
| Authors: | Ye, Cheong May Ariffin, Azhar Khan, Mohammad Niyaz |
| Issue Date: | Oct-2005 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. Cl.7 C07B41/00 |
| Abstract: | The nucleophilic second-order rate constant (kOH) for the reaction of OHˉ with Nˉ benzylphthalimide appears to follow a reaction mechanism similar to that for reactions of OHˉ with phthalimide and its N-alkylphthalimides. The rate of hydrolysis reveals an insignificant contribution of water-catalysed cleavage of NBPT compared with its hydroxide ion catalysed reaction. The observed pseudo first-order rate constant, kobs for alkaline hydrolysis of NBPT decreases with increase in the content of organic cosolvents (up to 70%, v/v) in mixed water-CH3CN and water-DMF solvents. |
| Page(s): | 2055-2059 |
| ISSN: | 0975-0975(Online); 0376-4710(Print) |
| Appears in Collections: | IJC-A Vol.44A(10) [October 2005] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCA 44A(10) 2055-2059.pdf | 1.01 MB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.