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http://nopr.niscpr.res.in/handle/123456789/21501| Title: | One pot reaction: Synthesis, characterization and biological activity of 3-alkyl/aryl-9- substituted 1,2,4-triazolo[3,4-b] [1,3,4]quinolinothiadiazepines |
| Authors: | Kalluraya, Balakrishna Gururaja, R. Rai, Ganesha |
| Issue Date: | Jan-2003 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Reaction of 6-substituted-2-chloro-3-formylquinoline 1 and 3-substituted-4-amino-5-mercapto-1,2,4-triazole 2 gave the novel thiadiazepine derivatives 5 rather than expected Schiff bases 4. Alternatively, compounds 5 were also prepared by the reaction of 2 with 6-substitutcri quinolones 3. The structures of the newly synthesized compounds have been proposed on the basis of elemental analysis, IR,1H NMR and mass spectral data. Some of the new synthetic compounds were also screened for their antibacterial and antifungal activity. Most of them showed significant activity. |
| Page(s): | 211-214 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.42B(01) [January 2003] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 42B(1) 211-214.pdf | 604.63 kB | Adobe PDF | View/Open |
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