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http://nopr.niscpr.res.in/handle/123456789/23263| Title: | Antioxidant and nitric oxide synthase activation properties of Ganoderma applanatum |
| Authors: | Acharya, Krishnendu Yonzone, Parinita Rai, Manjula Acharya, Rupa |
| Keywords: | Antioxidant activity;Ganoderma applanatum;Nitric oxide synthase |
| Issue Date: | Oct-2005 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | In vitro evaluation of antioxidant activities of Ganoderma applanatum showed significant inhibition of lipid peroxidation, and potent hydroxyl radical scavenging activity when compared with standard drug catechin. IC50 values of crude, boiled and ethanolic extracts of G. applanatum were 604.8, 624 and 267 μg/ml, respectively in case of hydroxyl radical scavenging activity, and 441, 520.5 and 166.16 μg/ml, respectively in case of lipid peroxidation. Furthermore, crude, boiled and ethanoiic extracts also increased significantly nitric oxide production (156.67, 121.88 and 742 pmole/mg dry wt/hr, respectively) over the control. The results of present investigation revealed that G. applanatum have potential therapeutic use. |
| Page(s): | 926-929 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.43(10) [October 2005] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 43(10) 926-929.pdf | 970.54 kB | Adobe PDF | View/Open |
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