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http://nopr.niscpr.res.in/handle/123456789/23354| Title: | Protective effect of Terminalia chebula against experimental myocardial injury induced by isoproterenol |
| Authors: | Suchalatha, S Devi, C S Shyamala |
| Keywords: | Isoproterenol;Lipid peroxide;Marker enzymes;Myocardial infarction;Terminalia chebula |
| Issue Date: | Feb-2004 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Cardioprotective effect of ethanolic extract of Terminalia chebula fruits (500 mg/kg body wt) was examined in isoproterenol (200 mg/kg body wt) induced myocardial damage in rats. In isoproterenol administered rats, the level of lipid peroxides increased significantly in the serum and heart. A significant decrease was observed in the activity of the myocardial marker enzymes with a concomitant increase in their activity in serum. Histopathological examination was carried out to confirm the myocardial necrosis. T. chebula extract pretreatment was found to ameliorate the effect of isoproterenol on lipid peroxide formation and retained the activities of the diagnostic marker enzymes. |
| Page(s): | 174-178 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.42(02) [February 2004] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 42(2) 174-178.pdf | 1.25 MB | Adobe PDF | View/Open |
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