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http://nopr.niscpr.res.in/handle/123456789/23633| Title: | Fructose, 1,6-diphosphate mitigates CCl4 suppressed nitric oxide synthase activity in rats |
| Authors: | Rao, M Rajeswara Kumari, K Vijaya Dass, P Jacob Vijaya, P Bharathi, P Vijaya |
| Issue Date: | Jan-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Effect of fructose 1 ,6-diphosphate (FOP) and carbon tetrachloride (CCl4) were studied individually and in combination on rat endothelial (ET) and smooth muscle cell (SMC) nitric oxide synthase (NOS) activities in vivo, inhibition of ET and SMC NOS activity in CCl4 treated rats was reversed in FDP+CCl4 treated animals. Cellular based NOS activity was significantly increased in FOP treated group of rats when compared to non treated controls. The results suggest a significant increase in NOS in rats treated with a combination of FOP+ CCl4 thus overcoming the suppression of NOS exposed to CCl4 alone. |
| Page(s): | 68-69 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.39(01) [January 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 39(1) 68-69.pdf | 349.81 kB | Adobe PDF | View/Open |
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