Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/24061| Title: | Characterization of toxin from cheilanthes fern and its effect on lymphocyte proliferation and DNA fragmentation |
| Authors: | Kumar, K Aswani Kataria, M Somvanshi, R Kumar, Satish Saini, Mohini |
| Issue Date: | Oct-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Thin layer chromatography of aqueous extract of whole Cheilanthes farinosa fern indicated the presence of ptaquiloside or ptaquiloside like compound, coinciding Rf values with that of Pterosin B standard. HPLC analysis revealed the presence of 26.3 mg/kg ptaquiloside. In vitro studies of the aqueous extract on lymphocyte culture revealed a correlation between stimulative indices and concentration of aqueous extract. Stimulation in lymphocyte proliferation was in order of bracken> cheilanthes > ConA> ptaquiloside standard. On incubation of lymphocyte with aqueous extract of ferns, no DNA damage was observed in isolated DNA. |
| Page(s): | 1065-1067 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.39(10) [October 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 39(10) 1065-1067.pdf | 663.85 kB | Adobe PDF | View/Open |
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