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http://nopr.niscpr.res.in/handle/123456789/26480| Title: | Synthesis and Antimicrobial Activity of Some New N-Methylpiperazinylthiadiazoles and Their Azetidinones |
| Authors: | Jaish, L Srivastava, S K |
| Issue Date: | Apr-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A series of 2-arylidenimino-5-( N4-methyl-Nl-piperazinylmethyl)-1 ,3,4-thiadiazole, 4, have been synthesized via condensation of 2-amino -5-(N4-methyl-N1-piperazinylmethyl)-1,3,4-thiadiazole with various carbonyl compounds. Cycloaddition of chloroacetyl chlorride to 4 gives 1-[5'-(N4- methyl-N1-piperazinylmethyl)-1', 3', 4'-thiadiazole-2'-yl]-4-substituted-3-chloro-2-azetidinones, 5. Compounds 4 and 5 have been screened for their antibacterial and antifungal activities. |
| Page(s): | 331-335 |
| ISSN: | 0975-1084 (Online); 0022-4456 (Print) |
| Appears in Collections: | JSIR Vol.60(04) [April 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| JSIR 60(4) 331-335.pdf | 707.11 kB | Adobe PDF | View/Open |
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