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http://nopr.niscpr.res.in/handle/123456789/30690| Title: | Synthesis of pyrazolines, isoxazolines and aminopyrimidines as biological potent agents |
| Authors: | Solankee, Anjani Thakor, Indrajit |
| Keywords: | Pyrazolines;Isoxazolines;Aminopyrimidines;Antimicrobial activity;Chalcones |
| Issue Date: | Feb-2006 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int.CI.7 C 07 D |
| Abstract: | Chalcones, 2-phenylamino-4-(4'-fluorophenylamino )-6-[4'-{3"-(phenyl/substituted phenyl/2"'- furanyl/3'"-pyridinyl)-2"- propenon-1"-y1} phenylamino]-s-triazines 6a-j have been prepared from ketone 5 based on s-triazine nucleus. These chalcones 6a-j on cyclisation with hydrazine hydrate, hydroxylamine hydrochloride and guanidine nitrate give the corresponding pyrazolines 7a-j, isoxazolines 8a-j and aminopyrirnidines 9a-j, respectively. Antimicrobial activities of all synthesized compounds have been performed by using cup-plate method against bacteria and by using poisoned food technique against fungi. The constitutions of newly synthesized compounds have been established on the basis of elemental analysis, IR and 1H NMR spectral data. |
| Page(s): | 517-522 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.45B(02) [February 2006] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(2) 517-522.pdf | 1.07 MB | Adobe PDF | View/Open |
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