Kinetics of oxidation of substituted 2-phenylthiazolidines by pyridinium chlorochromate

Abstract

Kinetics of oxidation of 2-phenylthiazolidine (PT) and substituted PI (SPT) by pyridinium chlorochromate (PCC) in dry acetic acid have been investigated. The reaction is first order in FCC and fractional order in PT and it exhibits Michaelis-Menten kinetic character. The complex formation constants (<em>K</em>) and the decomposition rate constants (<em>k</em>₁) have been computed from the double reciprocal plots of 1/<em>k</em>_obs versus 1/[PT]₀. The decomposition rate constants are not correlated by Hammett σ constants. Nevertheless, they show satisfactory correlation with σ₁ and σ₂ parameters. The correlation with Swain and Lupton F and R values is relatively less satisfactory.