Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/6682| Title: | Synthesis of some substituted azetidinonyl and thiazolidinonyl-1,3,4-thiadiazino[6,5-b]indoles as prospective antimicrobial agents |
| Authors: | Panwar, Hemant Verma, R S Srivastava, V K Kumar, Ashok |
| Keywords: | Benzylidenaminoindoles;azetidinon-3-yl-1,3,4-thiadiazino[6,5-b] indoles;antibacterial activity;antifungal activity |
| Issue Date: | Sep-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.8 C07D |
| Abstract: | Several 2-[(3-chloro-2-substituted phenyl)-4-azetidinon-3-yl]-1,3,4-thiadiazino[6,5-b]indoles and 2-[(2-substituted phenyl)-4-thiazolidinon-3-yl]-1,3,4-thiadiazino[6,5-b]indoles have been synthesized. The structures of the synthesized compounds are characterized by elemental and spectral analysis. These compounds are also evaluated for their antimicrobial susceptibility test against S.aureus, E.coli, K.pneumoniae, P.vulgaris and A.fumigatus, C.albicans, A. albicans ATCC, C. krusei G03 respectively. Compounds 4c and 5e showed the most potent antibacrerial and antifungal activities. These two compounds are devoid of any toxicity. |
| Page(s): | 2099-2104 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.45B(09) [September 2006] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(9) 2099-2104.pdf | 65.26 kB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.