Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/8976| Title: | A chiral pool based synthetic strategy for  -hydroxyalkyl- 2-butenolides |
| Authors: | Sengupta, Saumitra Mondal, Somnath |
| Issue Date: | Mar-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D 307/26 |
| Abstract: | A new stereoselective synthetic route to a -hydroxyalkyl-2-butenolide has been described starting from the  -hydroxy acid
chiral pool and via the intermediacy of an enantiopure -hydroxy- -ketosulfone. A
non-chelation controlled borohydride reduction (80% de) step is the key to the
high diastereoselectivity observed in this synthesis. |
| Page(s): | 553-556 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.44B(03) [March 2005] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 44B(3) 553-556.pdf | 57.42 kB | Adobe PDF | View/Open |
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