Tighter ion pair effect and scale-up study in microwave assisted aminolysis of enolizable esters using potassium <i style="">tert</i>-butoxide (<i style="">t</i>-BuOK)

Abstract

The tighter ion pair effect and scale-up study in aminolysis of enolizable esters using<b> </b>potassium <i style="">tert</i>-butoxide (<i style="">t</i>-BuOK) under microwave irradiations is described. This method provides synthetic advantages in terms of reaction time, product yields, eco-friendly environment and scale-up feasibility over the conventional heating method.